| Sim Time | Game Date | Type | Visiting Team | Home Team | Result | Game Action | Attendance |
|---|---|---|---|---|---|---|---|
| Mon Sep 22nd | October 8th | Exhibition | Jacksonville State | Southern Miss | W 58 - 62 | (play) | 529 |
| Tue Sep 23rd | October 10th | Exhibition | Southern Miss | Mississippi College | L 64 - 87 | (play) | 2,363 |
| Wed Sep 24th | October 12th | Exhibition | Southern Miss | Trevecca Nazarene | W 72 - 62 | (play) | 1,249 |
| Thu Sep 25th | October 16th | Non-Conference | Southern Miss | Pfeiffer | W 75 - 71 | (play) | 630 |
| Fri Sep 26th | October 19th | Non-Conference | Southern Miss | McMurry | W 87 - 74 | (play) | 1,140 |
| Sat Sep 27th | October 23rd | Non-Conference | Murray State | Southern Miss | L 79 - 72 | (play) | 913 |
| Sun Sep 28th | October 26th | Non-Conference | Southern Miss | Ouachita Baptist | L 66 - 86 | (play) | 2,884 |
| Mon Sep 29th | October 30th | Non-Conference | Texas Christian | Southern Miss | L 90 - 75 | (play) | 873 |
| Tue Sep 30th | November 2nd | Non-Conference | Southern Miss | Goucher | L 82 - 87 | (play) | 1,747 |
| Wed Oct 1st | November 6th | Non-Conference | Tarleton State | Southern Miss | L 75 - 57 | (play) | 998 |
| Thu Oct 2nd | November 9th | Non-Conference | Southern Miss | Eureka | L 61 - 66 | (play) | 1,323 |
| Fri Oct 3rd | November 13th | Non-Conference | #14 Lincoln University PA | Southern Miss | L 89 - 55 | (play) | 731 |
| Sat Oct 4th | November 16th | Non-Conference | Marymount | Southern Miss | W 76 - 80 | (play) | 772 |
| Sun Oct 5th | November 21st | Conference | Nichols | Southern Miss | W 53 - 88 | (play) | 700 |
| Mon Oct 6th | November 23rd | Conference | Southern Miss | Eastern Nazarene | W 73 - 65 | (play) | 751 |
| Tue Oct 7th | November 28th | Conference | Southern Miss | Eastern New Mexico | L 50 - 67 | (play) | 1,992 |
| Wed Oct 8th | November 30th | Conference | Arcadia | Southern Miss | W 68 - 90 | (play) | 978 |
| Thu Oct 9th | December 5th | Conference | Southern Miss | New England College | W 71 - 51 | (play) | 927 |
| Fri Oct 10th | December 7th | Conference | Southern Miss | Chowan | L 69 - 79 | (play) | 1,301 |
| Sat Oct 11th | December 12th | Conference | Southern Miss | Northern Iowa | W 79 - 63 | (play) | 583 |
| Sun Oct 12th | December 14th | Conference | Southern Miss | Missouri State | L 72 - 75 | (play) | 1,818 |
| Mon Oct 13th | December 19th | Conference | Southern Miss | North Carolina Wesleyan | L 90 - 91 | (play) | 1,408 |
| Tue Oct 14th | December 21st | Conference | Southern Miss | Oklahoma Christian | W 50 - 42 | (play) | 129 |
| Wed Oct 15th | December 26th | Conference | Cleveland State | Southern Miss | W 66 - 73 | (play) | 1,679 |
| Thu Oct 16th | December 28th | Conference | Southern Miss | Western New England | L 100 - 105 (ot) | (play) | 2,173 |
| Fri Oct 17th | January 2nd | Conference | Southern Miss | Texas A&M International | W 95 - 89 | (play) | 865 |
| Sat Oct 18th | January 4th | Conference | Southern Miss | Arkansas-Fort Smith | W 104 - 42 | (play) | 644 |
| Sun Oct 19th | January 9th | Conference | Southern Miss | John Carroll University | L 70 - 93 | (play) | 2,326 |
| Mon Oct 20th | January 11th | Conference | Southern Miss | Nichols | L 78 - 81 | (play) | 1,177 |
| Tue Oct 21st | January 16th | Conference | Eastern Nazarene | Southern Miss | W 55 - 82 | (play) | 996 |
| Wed Oct 22nd | January 18th | Conference | Eastern New Mexico | Southern Miss | W 66 - 74 | (play) | 1,457 |
| Thu Oct 23rd | January 23rd | Conference | Southern Miss | Arcadia | L 84 - 93 | (play) | 1,745 |
| Fri Oct 24th | January 25th | Conference | New England College | Southern Miss | L 68 - 58 | (play) | 1,319 |
| Sat Oct 25th | January 30th | Conference | Chowan | Southern Miss | L 82 - 80 (ot) | (play) | 1,436 |
| Sun Oct 26th | February 1st | Conference | Northern Iowa | Southern Miss | L 73 - 59 | (play) | 1,572 |
| Mon Oct 27th | February 6th | Conference | Missouri State | Southern Miss | W 72 - 92 | (play) | 1,086 |
| Tue Oct 28th | February 8th | Conference | North Carolina Wesleyan | Southern Miss | W 67 - 81 | (play) | 1,600 |
| Wed Oct 29th | February 13th | Conference | Oklahoma Christian | Southern Miss | W 41 - 75 | (play) | 1,277 |
| Thu Oct 30th | February 15th | Conference | Southern Miss | Cleveland State | W 91 - 83 (ot) | (play) | 1,081 |
| Fri Oct 31st | February 20th | Conference | Western New England | Southern Miss | L 76 - 67 | (play) | 1,715 |
| Sat Nov 1st | February 22nd | Conference | Texas A&M International | Southern Miss | W 79 - 87 | (play) | 1,825 |
| Sun Nov 2nd | February 27th | Conference | Arkansas-Fort Smith | Southern Miss | W 67 - 92 | (play) | 1,493 |
| Mon Nov 3rd | February 29th | Conference | John Carroll University | Southern Miss | L 101 - 69 | (play) | 1,330 |
| Tue Nov 4th | March 5th | Playoff | Cleveland State | Southern Miss | L 77 - 65 | (play) | 8,499 |
| Sat Nov 8th | March 12th | Invitational | Southern Miss | Cal State Monterey Bay | W 77 - 73 | (play) | 8,037 |
| Sun Nov 9th | March 14th | Invitational | Southern Miss | UH-Hilo | W 84 - 83 | (play) | 7,853 |
| Mon Nov 10th | March 19th | Invitational | St. Bonaventure | Southern Miss | W 68 - 70 | (play) | 8,493 |
| Tue Nov 11th | March 21st | Invitational | Arkansas Tech | Southern Miss | L 82 - 60 | (play) | 8,413 |